Percutaneous radiofrequency ablation of tumor feeding artery before target tumor ablation may reduce local tumor progression in hepatocellular carcinoma

摘要

BackgroundLocal tumor progression (LTP) in early-stage hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA) remains high. Tumor feeding artery ablation (FAA) before target tumor ablation was reported to reduce LTP in patients with HCC >3?cm. The aim of our study is to investigate whether FAA before target tumor ablation may reduce LTP in HCC MethodsWe retrospectively analysis the outcome of patients with HCC ResultsFAA significantly reduces LTP (FAA vs. non-FAA: local tumor progression 17.6% vs. 48.6%, p =?0.038), but not in intrahepatic recurrence: 29.4% vs. 25.7%, p =?0.778; or in overall recurrence rate: 41.2% vs. 62.9%, p =?0.14). The cumulative 1-year and 2-year LTP rates in FAA group were 17.6% and 17.6%, while 11.4% and 42.9% in non-FAA group ( p =?0.073), respectively. The cumulative overall recurrence rates at 1-year and 2-year were 29.4% and 35.3% in FAA group, while 14.3% and 57.1% in non-FAA group ( p =?0.130), respectively.ConclusionsFAA before target tumor ablation may decrease LTP in HCC