Higher neutrophil counts and neutrophil-to-lymphocyte ratio predict prognostic outcomes in?patients after non-atrial fibrillation-caused ischemic stroke

摘要

Abstract Background We aimed to determine whether higher neutrophil counts (NC) and neutrophil-to-lymphocyte ratio (NLR) were independently predictive of worse in-hospital outcome in patients after acute ischemic stroke (IS). Methods A retrospective observational study with prospective manner of {IS} registration. Between April 2012 and August 2014, a total number of 1731 patients with post-IS were consecutively enrolled in the study. Blood samples were drawn upon admission. Primary endpoint was in-hospital mortality. Secondary endpoint was severe stroke (≥16 NIHSS). Results The {NC} progressively increased from mild (NIHSS?≤?5) to moderate (NIHSS?≥?6?74% had a 2.54-fold increased risk of severe stroke (OR?=?1.82–3.54) compared to patients with {NC} <74%. Conclusion {NLR} was independently associated with in-hospital mortality and higher {NC} was independently predictive of severe stroke.