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Personalization Via CRM

机译:通过CRM进行个性化

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摘要

Since the mapping of the human genome more than a decade ago, pharmaceutical companies have been working on innovative ways to apply genomics to drug development. A classic example of success is the blood thinner Warfarin. Patients vary widely in their required Warfarin dose, and in the past this meant that initial doses for some patients were too high or too low, which led to negative side effects. However, by reading individual genetic markers, physicians can now accurately determine the best starting dose for each patient, potentially saving lives.
机译:自从十多年来对人类基因组进行定位以来,制药公司一直在研究将基因组学应用于药物开发的创新方法。成功的经典例子是血液稀释剂华法林。患者所需的华法林剂量差异很大,在过去,这意味着某些患者的初始剂量过高或过低,都会导致不良副作用。但是,通过读取单个遗传标记,医生现在可以准确地确定每位患者的最佳起始剂量,从而可能挽救生命。

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