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Haemodynamic conditions of patient-specific carotid bifurcation based on ultrasound imaging

机译:基于超声成像的患者特定颈动脉分叉的血流动力学条件

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摘要

The purpose of this paper is to complement the characterisation of patient-specific carotid artery bifurcation haemodynamics based on image data obtained by Doppler ultrasound imaging. A methodology for patient-specific 3D luminal surface reconstruction followed by structured hexahedral meshing of the volume and blood flow simulation is presented. Quantitative descriptors of the flow based on wall shear stress (WSS) are used to compare healthy and stenosed carotid bifurcation haemodynamic disturbances. Independently on the presence of stenosis, the internal carotid artery has been identified as a region of abnormal high values of oscillating shear index and relative residence time and low values of time averaged WSS. For the healthy carotid bifurcation, WSS descriptors manage to capture flow disturbances at the external carotid artery. This work addresses the lack of quantitative analysis on anatomically realistic stenosed carotid bifurcations.
机译:本文的目的是根据多普勒超声成像获得的图像数据来补充特定于患者的颈动脉分叉血流动力学的特征。提出了一种针对患者的3D腔表面重建的方法,然后进行了体积和血流模拟的结构化六面体网格划分。基于壁切应力(WSS)的流量的定量描述符用于比较健康的和狭窄的颈动脉分叉血流动力学紊乱。独立于狭窄的存在,颈内动脉已被确定为异常高的振荡剪切指数和相对滞留时间值以及低的时间平均WSS值区域。对于健康的颈动脉分叉,WSS描述子设法捕获颈外动脉的血流障碍。这项工作解决了对解剖学上现实的狭窄的颈动脉分叉的定量分析的问题。

著录项

  • 来源
    《Computer methods in biomechanics and bio》 |2014年第3期|157-166|共10页
  • 作者单位

    Faculdade de Engenharia, Instituto de Engenharia Mecanica (IDMEC-Polo FEUP), Universidade do Porto, Rua Roberto Frias s, 4200-465 Porto, Portugal;

    Faculdade de Engenharia, Instituto de Engenharia Mecanica (IDMEC-Polo FEUP), Universidade do Porto, Rua Roberto Frias s, 4200-465 Porto, Portugal;

    Faculdade de Engenharia, Instituto de Engenharia Mecanica (IDMEC-Polo FEUP), Universidade do Porto, Rua Roberto Frias s, 4200-465 Porto, Portugal;

    Faculdade de Engenharia, Instituto de Engenharia Mecanica e Gestao Industrial, Universidade do Porto, Rua Roberto Frias s, 4200-465 Porto, Portugal;

    Departamento de Neurologia, Hospital Sao Joao, Faculdade de Medicina, Universidade do Porto, Alameda Hernani Monteiro, 4200-319 Porto, Portugal;

    Departamento de Neurologia, Hospital Sao Joao, Faculdade de Medicina, Universidade do Porto, Alameda Hernani Monteiro, 4200-319 Porto, Portugal;

    Departamento de Neurologia, Hospital Sao Joao, Faculdade de Medicina, Universidade do Porto, Alameda Hernani Monteiro, 4200-319 Porto, Portugal;

    Faculdade de Engenharia, Instituto de Engenharia Mecanica e Gestao Industrial, Universidade do Porto, Rua Roberto Frias s, 4200-465 Porto, Portugal;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    carotid artery bifurcation; 3D reconstruction; mesh generation; computational fluid dynamics; image-based analysis;

    机译:颈动脉分叉;3D重建;网格生成;计算流体动力学;基于图像的分析;

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