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Analysis of a mechanical heart valve prosthesis and a native venous valve: Two distinct applications of FSI to biomedical applications

机译:机械心脏瓣膜假体和天然静脉瓣膜的分析:FSI在生物医学应用中的两个不同应用

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摘要

This paper reports the application of two commercial codes to the study of distinct cardiovascular problems: dynamics of a mechanical heart valve prosthesis and function of a native venous valve. The choice of code is driven by the characteristics of the problem. The ANSYS-CFX implicit finite volume code is employed for the mechanical valve where the solution is dominated by the interaction between the local fluid domain and the rigid valve leaflets. The LS-DYNA explicit dynamics code is used due to the stability of this approach when applied to systems with very flexible structural components such as the leaflets of a venous valve. The mechanical valve dynamics remain consistent for a range of mesh densities and residual criteria but begin to vary once the solution time step is increased above 2E-4 s. Venous valve function after application of a gravitational body load is shown to be dependent on parent vessel elastic modulus, E. The venous valve initially closes to a greater extent with a 'softer' parent vessel. Both approaches show promise for further study of these biomedical systems including the cavitation and thrombotic potential of mechanical valves and the local residence of blood constituents in the region of venous valve sinuses.
机译:本文报告了两个商业法规在研究独特的心血管问题中的应用:机械心脏瓣膜假体的动力学和天然静脉瓣膜的功能。代码的选择取决于问题的特征。机械阀采用ANSYS-CFX隐式有限体积代码,其解决方案以局部流体域与刚性阀瓣之间的相互作用为主导。由于此方法的稳定性,当将其应用于具有非常灵活的结​​构组件(例如,静脉瓣小叶)的系统时,将使用LS-DYNA显式动力学代码。机械阀动力学对于一定范围的网格密度和残留标准保持一致,但是一旦求解时间步长增加到2E-4 s以上,机械阀门动力学就会开始变化。施加重力负载后的静脉瓣膜功能显示取决于母血管弹性模量E。最初,“较软”的母血管会更大程度地关闭静脉瓣膜。两种方法都显示出对这些生物医学系统进行进一步研究的希望,包括机械瓣膜的气蚀和血栓形成潜力以及血液成分在静脉瓣膜窦区域的局部滞留。

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  • 作者单位

    Medical Physics Group, Department of Cardiovascular Science, University of Sheffield, Medical School, Beech Hill Road, Sheffield S10 2RX, U.K.;

    Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, U.K.;

    Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, U.K.;

    Technical University of Cluj Napoca, Electrical Engineering Faculty, Biomedical Engineering Center, 15, C. Daicoviciu Str., 400020 Cluj-Napoca, Romania;

    Medical Physics Group, Department of Cardiovascular Science, University of Sheffield, Medical School, Beech Hill Road, Sheffield S10 2RX, U.K.;

    Medical Physics Group, Department of Cardiovascular Science, University of Sheffield, Medical School, Beech Hill Road, Sheffield S10 2RX, U.K.;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    fluid-structure; valve; venous; mechanical;

    机译:流体结构阀;静脉机械;
  • 入库时间 2022-08-18 03:02:42

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