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UK BES has completed a viral vector suite facility for Cobra Biologies; a biologies specialist involved in COVID-19 vaccines. Located on Keele University campus, Cobra has invested in upgrading part of its existing development and production facility with 3 viral vector suites The project is a pivotal element of the company's commercial strategy and BES delivered the project four weeks ahead of schedule, despite the challenges of COVID-19. Compliant to ACDP Hazard Group and US BioSafety Level 2, along with FDA, EMA and MHRA standards, the new facilities will allow Cobra to work with customers to develop gene therapy treatments. The refurbishment project involved design and delivery of three grade C processing suites, each specified to contain a class 2 microbiological safety cabinet, for biological manipulations to be carried out in a grade A environment. Scientists will enter the new facilities via a primary change area to gain access to a grade C change area. Processing suites will be accessed via a clean corridor and exited into a 'dirty' corridor back to the primary change area.
机译:英国BES已经完成了COBRA生物学的病毒矢量套件设施;涉及Covid-19疫苗的生物学专家。 Cobra位于基尔大学校园内,COBRE投资于将其现有的开发和生产设施的一部分升级,其中3个病毒载体套件该项目是该公司的商业战略的关键因素,尽管有挑战,但仍然存在挑战新型冠状病毒肺炎(COVID-19):新冠肺炎(COVID-19):COVID-19。符合ACDP危险组和美国生物安全2级,以及FDA,EMA和MHRA标准,新设施将允许COBRA与客户合作开发基因治疗治疗。翻新项目涉及三级C加工套件的设计和交付,每个加工套件指定为含有2类微生物安全柜,用于在级别环境中进行的生物操作。科学家们将通过主要变更区域进入新设施,以获得C级变更区域。将通过干净的走廊访问加工套件,并将“脏”走廊进入“脏”走廊返回主要变更区域。

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    《Cleanroom technology》 |2020年第7期|68-101214|共6页
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