Preliminary study of three-tone paradigm Auditory P300 on aging dementia

摘要

Objective. To explore the changes of three-tone paradigm P300 nd observe the improvement of the dianos- tic sensitivity of P300 in aging dementia. Methods. Thirty-four patients of aging dementia underwent traditional P300 (2t-P300) and three-tone Paradigm auditory P300 (3t-P300). The results of these two methods were compared. Results. Abnormal P300 was found in 18 of 34 dementia cases (52.9 /100) by 2t-P300, and in 26 of 30 pa- Tients who finished the 3t-300 tests (86.7 /100). In 2t-P300, 9 of 24 mild cases, 7 of 8 moderate cases and 2 Severe cases showed abnormal results.