CLINICAL EFFECTS OF ROPIVACAINE MESYLATE IN EPIDURAL ANESTHESIA AND ANALGESIA

摘要

Since the report that ropivacaine hydrochloride, a new amide local anesthetic, is of lower cardiac toxi-city both in animals and humans, several studies have shown it to be a clinically effective local anesthetic widely used for both epidural anesthesia and analgesia. Ropivacaine mesylate made in China is structurally from ropivacaine hydrochloride by substituting a mesylate group for hydrochloride group. This study was designed to clinically provide a double-blind comparison of ropivacaine mesylate with ropivacaine hydrochloride in epidural anesthesia and analgesia.