A method for reducing or inhibiting respiratory depression in a subject; A method for inducing analgesia, anesthesia or sedation in a subject by simultaneously reducing or inhibiting respiratory depression in the subject; AND PHARMACEUTICAL COMPOSITION FOR INDUCING ANALGESIA, ANESTHESIA OR SEDATION IN A SUBJECT ...

摘要

The invention is directed to a method for alleviating respiratory depression in a subject as a result of disease of pharmacological agents such as opiates, opioids or barbiturates. The invention also discloses pharmaceutical compositions for use with the method, the composition containing in combination, an analgesic, anaesthetic, or a sedative and a positive allosteric AMPA receptor modulator in an amount sufficient to reduce or inhibit respiratory depression caused by the analgesic, anaesthetic, or sedative.