Histochemical and immunohistochemical studies of distribution of acetylcholinesterase-positive and peptidergic terminals in the nasal mucosa of rats

摘要

Conclusions ACHE-positive (corresponding to parasympathetic nerves) and peptidergic terminals have different distribution patterns in the nasal mucosa of rats, although an overlap does exist, indicative of their different physiological effects on the regulation of nasal secretion and other functions; AChE and multiple neuropeptides in the cytoplasm of TG cells might play a role in modulating the nasal secretion in response to stimuli in the nasal mucosa. Objective To further investigate the mechanism of nasal secretion closely related to the innervation pat- terns in nasal mucosa with emphasis on the acetyl- cholinesterase (AChE)-positive fibers ad peptidergic terminals in nasal mucosa as well as trigeminal ganglion (TG) cells.