The effects of fibroblast growth factors on ischemic kidney, liver and gut injuries

摘要

Conclusions The protective effects of FGFs may come from the non-mitogenic effects of FGFs at the early and the mitogenic effects at the late stage of tissue repair. These results indicate a potential for clini- cal use of FGFs as a therapeutic modality in ischemic visceral organ injuries in the future. Objective To explore the possibility of reducing reperfusion injuries of internal organ with acidic and basic fibroblast growth factors (aFGF and bFGDF). Methods Tow kinds of ischemia and reperfusion Animal models were used in this study.