Juxtaglomerular cell tumor of the kidney: a clinicopathological analysis of five cases

摘要

Juxtaglomerular cell tumor (JGCT) is a kind of rare renal neoplasm that was first described by Robertson in 1967. This tumor typically is found in young adults, and patients usually have hypertension, hyperaldosteronism and hypokalemia secondary to tumor renin secretion. To our knowledge, only about 70 cases have been reported including no more than 8 cases in China. Because of its rarity, the clinicopathological features of the tumor have not been clearly established. In this article, 5 cases of JGCT were reported, in order to give a better understanding of its morphological and immunohistochemical profiles. In addition, the immunophenotypical findings of JGCT were compared with 5 cutaneous glomus tumors and 5 hemangiopericytomas, which shared morphological features with JGCT.