Study on TCM syndrome-typing of chronic ulcera-tive colitis

摘要

AIMS To study the relationship between the modern clinical and pathohistologicai classification and TCM Syndrome-Typing of chronic ulcerative colitis (CUC). METHODS Totally 452 patients with CUC were classified according to the standards of TCM Syndrome-Typing set up in the Conference of the Combination of the Chinese-Western Medicine on Digestive Diseases in Linfen. The relevant changes between both classifications were analyzed and compared through the colonofiberscopic and pathohistologicai examination. RESULTS The type of retention of damp-heat in interior is more commonly seen in the patients with initial onset of disease (P < 0.01). There is no significant difference among other TCM Syndrome-Typing groups in patients with chronic persistent and recurrent disease (P > 0.05). The congestion, edema, reduction of goblet cells and the infiltration of neutrophils are pathologically common to all TCM Syndrome-Typing groups. Mucosal ulcer is dominant in damp-heat syndrome while crypt ulcer is dominant in the types of spleen-stomach asthenia and spleen-kidney Yang deficiency ( P < 0.01). CONCLUSIONS There appears a certain relationship between the TCM syndrome typing and pathohistologicai changes of the colonal mucosa of CUC.