Study on combined assay for serum tumor markers in patients with hepatic carcinoma

摘要

Since the hepatic solid-occupying lesion (HSOL) was found by both ultrasonoscopy (US) and computed tomography (CT). If the customary alpha-fetoprotin (AFP) standard for diagnosis primary hepatic carcinoma is used, those cancers with lower AFP concentration may miss the diagnosis. On the other hand, the use of the standard: AFP-positive (≥ 20 μg/L ) + HSOL = primary hepatocellular carcinoma (PHCC), may yield false positive results. In order to elevate both the preoperative and differential diagnosis levels for hepatic carcinoma, we assayed combindedly the preoperative levels of serum AFP, carbohydrate antibody (CA) 19-9 and carcinoembryonic antigen (CEA) in the patients with HSOL.