Synthesis and hemocopatibilities of new segmented polyurethanes and poly(urethane urea)s with poly(butadiene) and phosphatidylcholine analogues in the main chains and long-chain alkyl groups in the side chains

摘要

Three new phospholipid diols bis[2-(2-hydroxyethyldimethylammonio) ethyl] diethylene octadecylamine diphosphate (BDDODP), bis[2-(2-hydroxyethyldimethylammonio) ethyl] diethylene hexadecylamine diphosphate (BDDODP), and bis[2-(2-hydroxyethyldimethylammonio) ethyl] diethylene hexadecylamine dodecylamine diphosphate (BDDODP),together with 1, 4-butanediol (BD) or ethylenediamine (ED) as chain extender ware further incorporated into the prepolymer of poly(butadiene) glycol(PBD) and 4, 4'-methylenediphenyl diisocyanate (MDI).