Fluorescent gold nanoparticles-based fluorescence sensor for Cu~(2+) ions

摘要

A new fluorescence sensor for the highly selective detection of Cu~(2+) ion with a detection limit of 3.6 nM based on the aggregation-induced fluorescence quenching of the highly fluorescent glutathione-capped gold nanoparticles is reported.rnThe study of gold nanoparticles (AuNPs) is one of the most exciting research fields in nanotechnology owing to its extensive applications for biosensor fabrication. In this area, a number of colorimetric assays have been developed taking advantage of the extremely high extinction coefficients and the strongly distance-dependent surface plasmon resonance (SPR) absorption of AuNPs. In these assays, AuNPs solution generally exhibits a color change from red to blue because of the shift of the SPR band to longer wavelength when the nanoparticles are in the aggregated state.