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Molecularly imprinted nanotubes for enantioselective drug delivery and controlled release

机译:分子印迹纳米管用于对映选择性药物递送和控释

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摘要

Molecularly imprinted nanotubes for enantioselective drug delivery and controlled release are fabricated by the combination of template synthesis and ATRP grafting. The release of R-propranolol from the imprinted nanotubes in rats is restricted while the release of pharmacologically active S-enantiomer is greatly promoted.
机译:通过模板合成和ATRP接枝相结合,制备了用于对映选择性药物递送和控释的分子印迹纳米管。 R-普萘洛尔从印迹的纳米管在大鼠中的释放受到限制,而药理活性S-对映异构体的释放则大大促进。

著录项

  • 来源
    《Chemical Communications》 |2010年第41期|p.7688-7690|共3页
  • 作者单位

    State Key Laboratory of Environmental Chemistry andEcotoxicology, Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences, Beijing, 100085, China;

    rnBNLMS, Institute of Chemistry, Chinese Academy of Sciences,Beijing, 100090, China;

    rnBNLMS, Institute of Chemistry, Chinese Academy of Sciences,Beijing, 100090, China College of Pharmacy, Hebei University, Baoding, 071002, China;

    rnState Key Laboratory of Environmental Chemistry andEcotoxicology, Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences, Beijing, 100085, China;

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  • 入库时间 2022-08-17 13:24:17

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