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A facile scanometric strategy for ultrasensitive detection of protein using aptamer-initiated rolling circle amplification

机译:使用适体启动的滚环扩增技术进行蛋白质超灵敏检测的简便扫描方法

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摘要

A pragmatic and simple strategy was developed for ultrasensitive detection of protein with good specificity and low matrix effect, which combined aptamer-initiated rolling circle amplification with a Au nanoparticle probe and convenient scanometric readout.
机译:开发了一种实用且简单的策略,用于蛋白质的超灵敏检测,具有良好的特异性和较低的基质效应,将适体启动的滚环扩增与Au纳米颗粒探针相结合,并具有便捷的扫描读数。

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  • 来源
    《Chemical Communications》 |2010年第36期|P.6720-6722|共3页
  • 作者单位

    Key Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, P.R. China Laboratory of Laboratory Medical Diagnostics (Ministry of Education of China), Department of Key Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China;

    rnKey Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, P.R. China;

    rnKey Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, P.R. China;

    Jiangsu Institute of Cancer Prevention and Cure, Nanjing 210009, P.R. China;

    rnKey Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, P.R. China Laboratory of Laboratory Medical Diagnostics (Ministry of Education of China), Department of Key Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China;

    rnLaboratory of Laboratory Medical Diagnostics (Ministry of Education of China), Department of Key Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P.R. China;

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