5-Hydroxy-2,2,6,6-tetramethyl-4-(2-methylprop-l-en-yl)cyclohex-4-ene-1,3-dione, a novel cheletropic trap for nitric oxide EPR detection

摘要

The title compound behaves as an efficient cheletropic trap for both NO and NO_2 radicals in the presence of oxygen, yielding EPR observable nitroxide and alkoxynitroxide, respectively.rnNitrogen monoxide (or nitric oxide) is a small gaseous radical involved in a wide range of biological processes, such as neurotransmission, immune defence or blood flow regulation. The lack of a signal for free NO in solution and its short physiological lifetime preclude its direct electron paramagnetic resonance (EPR) observation.