MgI_2-accelerated enantioselective Morita-Baylis-Hillman reactions of cyclopentenone utilizing a chiral DMAP catalyst

摘要

Fu's planar chiral DMAP catalyst efficiently promotes the asymmetric Morita-Baylis-Hillman reactions of cyclopentenone with a variety of aldehydes in the presence of MgI_2 as a cocatalyst.The Morita-Baylis-Hillman (MBH) reaction, first reported in 1968, is an important carbon-carbon bond-forming reaction between electron-deficient alkenes, such as α,β-unsaturated ketones, and aldehydes or activated ketones.