Tunable stereoselective alkene synthesis by treatment of activated imines with nonstabilized phosphonium ylides

摘要

A broad range of readily accessible N-sulfonyl imines undergo olefination reaction with nonstabilized phosphonium ylides under mild conditions to afford an array of both Z- and E-isomers of 1,2-disubstituted alkenes, ally lie alcohols, and allylic amines in good yields and with greater than 99 : 1 stereoselectivity.