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首页> 外文期刊>Chemical Communications >A potential water-soluble ytterbium-based porphyrin-cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy
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A potential water-soluble ytterbium-based porphyrin-cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy

机译：高尔基体成像和光动力疗法的潜在水溶性water基卟啉-周期双生物探针

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摘要

An amphiphilic water-soluble ytterbium complex which is photo-selective, functional and Golgi apparatus specific has been designed as a responsive dual probe capable of sensitizing emission within the biological window (660 and 750 nm), generating the singlet oxygen (Φ_△ = 0.45) and triggering local cell damage only upon exposure to visible and near-infrared laser excitation.
机译：已设计出一种具有光选择性，功能性和高尔基体特异性的两亲水溶性complex配合物，作为能够敏化生物窗口（660和750 nm）内发射并产生单线态氧（Φ_△= 0.45）的响应双探针。 ）并仅在暴露于可见光和近红外激光激发下才触发局部细胞损伤。

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  • 来源
    《Chemical Communications》 |2012年第77期|p.9646-9648|共3页
  • 作者

    Jing-Xiang Zhang; Hongguang Li; Chi-Fai Chan; Rongfeng Lan; Wai-Lun Chan; Ga-Lai Law; Wai-Kwok Wong; Ka-Leung Wong;

  • 作者单位

    Department of Chemistry, Hong Kong Baptist University,Kowloon Tong, Hong Kong SAR, P. R. China,Department of Chemistry, Hanshan Normal University, Chaozhou,Guangdong Province, P. R. China,These authors contributed equally and served as co-lst authors;

    Department of Chemistry, Hong Kong Baptist University,Kowloon Tong, Hong Kong SAR, P. R. China,These authors contributed equally and served as co-lst authors;

    Department of Chemistry, Hong Kong Baptist University,Kowloon Tong, Hong Kong SAR, P. R. China,These authors contributed equally and served as co-lst authors;

    Department of Chemistry, Hong Kong Baptist University,Kowloon Tong, Hong Kong SAR, P. R. China;

    Department of Chemistry, Hong Kong Baptist University,Kowloon Tong, Hong Kong SAR, P. R. China;

    Department of Applied Biology and Chemical Technology,Hong Kong Polytechnic University, Hong Hum, Hong Kong SAR,P. R. China;

    Department of Chemistry, Hong Kong Baptist University,Kowloon Tong, Hong Kong SAR, P. R. China;

    Department of Chemistry, Hong Kong Baptist University,Kowloon Tong, Hong Kong SAR, P. R. China;

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