A novel oxidative transformation of alcohols to nitriles: an efficient utility of azides as a nitrogen source

摘要

An efficient methodology to oxidize benzylic and cinnamyl alcohols to their corresponding nitriles in excellent yields has been developed. This methodology employs DDQ as an oxidant and TMSN_3 as a source of nitrogen in the presence of a catalytic amount of Cu(ClO_4)2·6H_2O.