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Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging

机译:叶酸官能化的荧光金纳米簇,聚合物作为连接物用于癌细胞成像

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摘要

A novel nano-conjugate containing ultrasmall water-soluble AuNCs protected by ovalbumin as the fluorescent part, folic acid as the targeting ligand and a homopolymer N-acryloxysuccinimide as the linker has been investigated. Moreover, specific staining of HeLa cells by the nano-conjugate has been demonstrated.
机译:研究了一种新型纳米共轭物,该纳米共轭物包含由卵白蛋白作为荧光部分保护,叶酸作为靶向配体和均聚物N-丙烯酰氧基琥珀酰亚胺作为接头的超小型水溶性AuNCs。此外,已经证明了纳米缀合物对HeLa细胞的特异性染色。

著录项

  • 来源
    《Chemical Communications》 |2013年第73期|8030-8032|共3页
  • 作者单位

    Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems Institute of Chemistry, Chinese Academy of Sciences, No. 2 Zhongguancun Beiyijie, 100190, P. R. China;

    Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems Institute of Chemistry, Chinese Academy of Sciences, No. 2 Zhongguancun Beiyijie, 100190, P. R. China,Graduate School, University of Chinese Academy of Sciences, 19A Yuquanlu,Beijing, 100049, P. R. China;

    Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems Institute of Chemistry, Chinese Academy of Sciences, No. 2 Zhongguancun Beiyijie, 100190, P. R. China;

    Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems Institute of Chemistry, Chinese Academy of Sciences, No. 2 Zhongguancun Beiyijie, 100190, P. R. China,Graduate School, University of Chinese Academy of Sciences, 19A Yuquanlu,Beijing, 100049, P. R. China;

    Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems Institute of Chemistry, Chinese Academy of Sciences, No. 2 Zhongguancun Beiyijie, 100190, P. R. China;

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  • 入库时间 2022-08-17 13:18:37

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