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A ratiometric fluorescent dye for the detection of glutathione in live cells and liver cancer tissue

机译:用于检测活细胞和肝癌组织中谷胱甘肽的比例荧光染料

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摘要

A novel ratiometric biothiol probe Glutathione Green was developed. It allows quantitative measurement of glutathione in cell extracts and direct visualization of changes in glutathione levels in live cells. Remarkably, this is the first reported biothiol probe which can detect the carcinoma region of liver tissue based on the differences in the glutathione level.
机译:新型比例生物硫醇探针谷胱甘肽绿色被开发。它可以定量测量细胞提取物中的谷胱甘肽,并直接观察活细胞中谷胱甘肽水平的变化。值得注意的是,这是首次报道的生物硫醇探针,可以根据谷胱甘肽水平的差异检测肝脏组织的癌区域。

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  • 来源
    《Chemical Communications》 |2013年第65期|7207-7209|共3页
  • 作者单位

    Department of Chemistry and MedChem Program, Life Sciences Institute,National University of Singapore, 3 Science Drive 3, Singapore 117543;

    Laboratory of Bioimaging Probe Development, Singapore Bioimaging Consortium (SBIC), Agency for Science, Technology and Research (A*STAR), #02-02 Helios,11 Biopolis Way, Biopolis, Singapore 138667;

    Laboratory of Bioimaging Probe Development, Singapore Bioimaging Consortium (SBIC), Agency for Science, Technology and Research (A*STAR), #02-02 Helios,11 Biopolis Way, Biopolis, Singapore 138667;

    Department of Chemistry and MedChem Program, Life Sciences Institute,National University of Singapore, 3 Science Drive 3, Singapore 117543,Laboratory of Bioimaging Probe Development, Singapore Bioimaging Consortium (SBIC), Agency for Science, Technology and Research (A*STAR), #02-02 Helios,11 Biopolis Way, Biopolis, Singapore 138667;

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  • 入库时间 2022-08-17 13:18:31

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