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A vitamin-responsive mesoporous nanocarrier with DNA aptamer-mediated cell targeting

机译：具有DNA适体介导的细胞靶向作用的维生素反应性介孔纳米载体

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摘要

A smart drug delivery system with cancer cell targeting and biorespon-sive controlled drug release has been constructed by taking advantage of a protein-capped mesoporous nanovalve and a DNA aptamer.
机译：通过利用蛋白质封端的介孔纳米阀和DNA适体，构建了具有癌细胞靶向和生物反应性受控药物释放的智能药物输送系统。

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  • 来源
    《Chemical Communications》 |2013年第52期|5823-5825|共3页
  • 作者

    Le-Le Li; Mengying Xie; Jie Wang; Xinyang Li; Cheng Wang; Quan Yuan; Dai-Wen Pang; Yi Lu; Weihong Tan;

  • 作者单位

    Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China,Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA;

    Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China;

    Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China;

    Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China;

    Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China;

    Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China;

    Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China;

    Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA;

    Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center and UF Genetics Institute, Center for Research at the Bio/Nano Interface, University of Florida, Gainesville, Florida 32611-7200, USA,State Key Laboratory for Chemo/Bio-Sensing and Chemometrics, College of Biology, and College of Chemistry and Chemical Engineering Hunan University, Changsha 410082, China;

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  • 入库时间 2022-08-17 13:18:26

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