Gold nanoparticle cluster-plasmon-enhanced fluorescent silica core-shell nanoparticles for X-ray computed tomography-fluorescence dual-mode imaging of tumors

Koichiro Hayashi; Michihiro Nakamura; Hirokazu Miki; Shuji Ozaki; Masahiro Abe; Toshio Matsumoto; Kazunori Ishimura

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Gold nanoparticle cluster-plasmon-enhanced fluorescent silica core-shell nanoparticles for X-ray computed tomography-fluorescence dual-mode imaging of tumors

机译：金纳米粒子簇-等离激元增强的荧光二氧化硅核-壳纳米粒子用于肿瘤的X射线计算机断层扫描-荧光双模成像

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摘要

Owing to the surface plasmon resonance-enhanced electromagnetic field, clustered gold nanoparticles-fluorescent silica core-shell nanoparticles became excited within the therapeutic window and fluoresced strongly in this window. The nanoparticles enabled tumor detection using fluorescence imaging and X-ray computed tomography.

机译：由于表面等离子体共振增强的电磁场，聚集的金纳米颗粒-荧光二氧化硅核-壳纳米颗粒在治疗窗内被激发并在该窗中强烈发荧光。纳米颗粒能够使用荧光成像和X射线计算机断层摄影术进行肿瘤检测。

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《Chemical Communications》 |2013年第46期|5334-5336|共3页
作者
Koichiro Hayashi; Michihiro Nakamura; Hirokazu Miki; Shuji Ozaki; Masahiro Abe; Toshio Matsumoto; Kazunori Ishimura;
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作者单位

Department of Anatomy and Cell Biology, Institute of Health Biosciences,The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima,770-8503, Japan;

Department of Anatomy and Cell Biology, Institute of Health Biosciences,The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima,770-8503, Japan;

Division of Transfusion Medicine, Tokushima University Hospital,2-50-1 Kuramoto-cho, Tokushima, 770-0042, Japan;

Department of Internal Medicine, Tokushima Prefectural Central Hospital,1-10-3 Kuramoto-cho, Tokushima, 770-0042, Japan;

Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Medical Sciences, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan;

Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Medical Sciences, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan;

Department of Anatomy and Cell Biology, Institute of Health Biosciences,The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima,770-8503, Japan;

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入库时间 2022-08-17 13:18:24

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1. Quantitative imaging of gold nanoparticle distribution in a tumor-bearing mouse using benchtop x-ray fluorescence computed tomography [J] . Nivedh Manohar, Francisco J. Reynoso, Parmeswaran Diagaradjane, Scientific reports. . 2016,第1期

机译：使用台式X射线荧光计算机断层扫描技术对荷瘤小鼠中金纳米颗粒分布的定量成像
2. X-ray computed tomography imaging of a tumor with high sensitivity using gold nanoparticles conjugated to a cancer-specific antibody via polyethylene glycol chains on their surface [J] . Tomohiko Nakagawa, Kohsuke Gonda, Takashi Kamei, Science and technology of advanced materials . 2016,第1期

机译：X射线计算机断层扫描成像技术，通过使用通过其表面上的聚乙二醇链与癌症特异性抗体结合的金纳米颗粒，可以对肿瘤进行高灵敏度的成像
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机译：X射线计算机断层扫描成像技术，通过使用通过其表面上的聚乙二醇链与癌症特异性抗体结合的金纳米颗粒，可以对肿瘤进行高灵敏度的成像
4. Feasibility of X-ray Fluorescence Computed Tomography (XFCT) Imaging of Human Lung Tumors loaded with Gold Nanoparticles: A Monte Carlo Study [C] . Md Foiez Ahmed, Sandun Jayarathna, Sang Hyun Cho International Conference on Nano/Molecular Medicine and Engineering . 2019

机译：X射线荧光计算断层扫描（XFCT）成像的人肺肿瘤成像，载有金纳米颗粒：蒙特卡罗研究
5. Functionalized gold nanoparticles as damage-specific x-ray computed tomography contrast agents in bone tissue. [D] . Ross, Ryan D. 2011

机译：功能化的金纳米颗粒作为骨组织中特定于损伤的X射线计算机断层扫描造影剂。
6. X-ray computed tomography imaging of a tumor with high sensitivity using gold nanoparticles conjugated to a cancer-specific antibody via polyethylene glycol chains on their surface [O] . Tomohiko Nakagawa, Kohsuke Gonda, Takashi Kamei, 2016

机译：使用金纳米颗粒通过其表面上的聚乙二醇链与癌症特异性抗体偶联的X射线计算机断层摄影术成像
7. Iodinated silica/porphyrin hybrid nanoparticles for X-ray computed tomography/fluorescence dual-modal imaging of tumors [O] . Koichiro Hayashi, Sakamoto Wataru, Toshinobu Yogo 2014

机译：碘化二氧化硅/卟啉杂化纳米粒子用于X射线计算机断层扫描/荧光双模态肿瘤成像

Gold nanoparticle cluster-plasmon-enhanced fluorescent silica core-shell nanoparticles for X-ray computed tomography-fluorescence dual-mode imaging of tumors

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