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Visible light induced fast synthesis of protein-polymer conjugates: controllable polymerization and protein activity

机译:可见光诱导的蛋白质-聚合物结合物的快速合成:可控的聚合和蛋白质活性

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摘要

Herein visible tight is used to induce RAFT polymerization from protein for preparing protein-polymer conjugates at ambient temperature. Polymerization is fast and can be conveniently controlled with irradiation time. By site-specific polymerization of NIPAm to protein, the protein activity is maintained and in certain cases it presents an efficient on-off-switchable property.
机译:本文使用可见的致密物从蛋白质诱导RAFT聚合,以在环境温度下制备蛋白质-聚合物缀合物。聚合反应快,可以方便地控制照射时间。通过将NIPAm进行位点特异性聚合成蛋白质,可以维持蛋白质活性,并且在某些情况下,它可以提供有效的开关特性。

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  • 来源
    《Chemical Communications》 |2014年第49期|6506-6508|共3页
  • 作者单位

    The Key Lab of Health Chemistry and Molecular Diagnosis of Suzhou, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, P. R. China;

    The Key Lab of Health Chemistry and Molecular Diagnosis of Suzhou, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, P. R. China;

    The Key Lab of Health Chemistry and Molecular Diagnosis of Suzhou, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, P. R. China,Center for Soft Condensed Matter Physics and Interdisciplinary Research, Soochow University, Suzhou, 215006, P. R. China;

    Department of Chemistry, University of Warwick, Coventry, CV47AL, UK;

    The Key Lab of Health Chemistry and Molecular Diagnosis of Suzhou, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, P. R. China;

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  • 入库时间 2022-08-17 13:15:54

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