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Proteome reactivity profiling for the discrimination of pathogenic bacteria

机译:蛋白质组反应性谱分析可鉴别致病菌

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摘要

Diverse proteome reactivity profiles were obtained using small-molecule electrophiles. Based on the cross-reactivity profile, each protein generated a unique reactivity fingerprint. Here, we report the first proteome reactivity signature-based discrimination of 11 bacteria. Perfect differentiation of 11 bacteria can be achieved using 2 benzyt-halide probes.
机译:使用小分子亲电试剂获得不同的蛋白质组反应性概况。基于交叉反应谱,每种蛋白质均产生独特的反应指纹。在这里,我们报告第一个基于蛋白质组反应性签名的11种细菌的区分。使用2种苄基卤化物探针可以实现11种细菌的完美分化。

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  • 来源
    《Chemical Communications》 |2014年第33期|4347-4350|共4页
  • 作者单位

    Molecular Recognition Research Center, Korea Institute of Science and Technology(KIST), 39-1 Hawolgok-dong, Seoul, 136-791, Korea,University of Science & Technology, 113 Gwahank-ro, Yuseong-gu, Daejeon 305-333, Korea;

    Molecular Recognition Research Center, Korea Institute of Science and Technology(KIST), 39-1 Hawolgok-dong, Seoul, 136-791, Korea;

    Molecular Recognition Research Center, Korea Institute of Science and Technology(KIST), 39-1 Hawolgok-dong, Seoul, 136-791, Korea;

    Molecular Recognition Research Center, Korea Institute of Science and Technology(KIST), 39-1 Hawolgok-dong, Seoul, 136-791, Korea;

    Nanormics Inc., 10-57 Hawolgokdong, Seoul 136-865, Korea;

    Molecular Recognition Research Center, Korea Institute of Science and Technology(KIST), 39-1 Hawolgok-dong, Seoul, 136-791, Korea;

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  • 入库时间 2022-08-17 13:15:29

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