Continuous hydrogenation reactions in a tube reactor packed with Pd/C

摘要

Continuous flow of the substrate solution and hydrogen gas through a tube reactor packed with Pd/C catalyst brings about a highly reactive and efficient hydrogenation system, which converts 4-cyanobenzaldehyde to the benzyl alcohol derivatives at 25 degreesC, and at 90 degreesC, the cyano group becomes reduced to give the corresponding amine and toluene derivatives within 2 min.