Synthesis and structural characterization of cross-linked histidine-phenol Cu(Ⅱ) complexes as cytochrome c oxidase active site models

摘要

Tridentate cross-linked histidine-phenol Cu(n) ether and ester complexes, chemical analogs of the active site of several heme-copper oxidases, have been synthesized and crystallized.rnThe role of the post-translationally modified tyrosine in the heme-copper oxidases continues to be a subject of great interest.