Downregulation of CuZn-superoxide dismutase contributes to β-adrenergic receptor-mediated oxidative stress in the heart

Sanjay Srivastava; Bysani Chandrasekar; Yan Gu; Jianzhu Luo; Tariq Hamid; Bradford G. Hill; and Sumanth D. Prabhu

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Downregulation of CuZn-superoxide dismutase contributes to β-adrenergic receptor-mediated oxidative stress in the heart

机译：CuZn超氧化物歧化酶的下调有助于心脏中β-肾上腺素受体介导的氧化应激

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Objective: Sustained β-adrenergic receptor (β-AR) activation augments oxidative stress in the heart; whether alterations in antioxidant enzymes contribute to this effect is unknown.

机译：目的：持续的β-肾上腺素受体（β-AR）活化会增加心脏的氧化应激。尚不清楚抗氧化剂酶的改变是否有助于这种作用。

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《Cardiovascular Research》 |2007年第3期|445-455|共11页
作者
Sanjay Srivastava; Bysani Chandrasekar; Yan Gu; Jianzhu Luo; Tariq Hamid; Bradford G. Hill; and Sumanth D. Prabhu;
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作者单位

Louisville VAMC and Institute of Molecular Cardiology Department of Medicine University of Louisville Louisville KY United States;

Medicine/Cardiology University of Texas Health Science Center San Antonio TX United States;

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1. Effects of oxidative stress on expression of extracellular superoxide dismutase, CuZn-superoxide dismutase and Mn-superoxide dismutase in human dermal fibroblasts [J] . P Str?lin, S L Marklund The biochemical journal . 1994,第2期

机译：氧化应激对人皮肤成纤维细胞细胞外超氧化物歧化酶，铜锌超氧化物歧化酶和锰超氧化物歧化酶表达的影响
2. Maintenance of Normal Stress Tolerance in the Moss Physcomitrella patens Lacking Chloroplastic CuZn-Superoxide Dismutase [J] . Yuya Higashi, Katsuaki Takechi, Hiroyoshi Takano, American Journal of Plant Sciences . 2015,第5期

机译：缺乏光塑性CuZn-超氧化物歧化酶的苔藓小藓藓中正常胁迫耐性的维持
3. CuZn-Superoxide Dismutase in Brain of Rats Exposed to Acute, Chronic or Combined Stress [J] . S. Pajovi?, A. Todorovi?, S. Peji?, Biotechnology & Biotechnological Equipment . 2006,第1期

机译：暴露于急性，慢性或联合应激的大鼠脑中的铜锌超氧化物歧化酶
4. Chroloplast CuZn-superoxide dismutase and catalase are earliest targets of osmotic stress in lettuce plants [C] . Y Domae, E Nawata, S Kanematsu, International Congress on Photosynthesis . 2001

机译：慢血糖血糖Cuzn-超氧化物歧化酶和过氧化氢酶是莴苣植物中渗透胁迫的最早靶向
5. Heat stress induces downregulation of hippocampal superoxide dismutase-1: A possible mechanism for heat-related neuronal cell death. [D] . El-Orabi, Naglaa. 2006

机译：热应激诱导海马超氧化物歧化酶-1的下调：与热相关的神经元细胞死亡的可能机制。
6. Effects of oxidative stress on expression of extracellular superoxide dismutase CuZn-superoxide dismutase and Mn-superoxide dismutase in human dermal fibroblasts. [O] . P Strålin, S L Marklund 1994

机译：氧化应激对人皮肤成纤维细胞细胞外超氧化物歧化酶铜锌超氧化物歧化酶和锰超氧化物歧化酶表达的影响。
7. Downregulation of CuZn-superoxide dismutase contributes to β-adrenergic receptor-mediated oxidative stress in the heart [O] . S SRIVASTAVA, B CHANDRASEKAR, Y GU, 2007

机译：Cuzn-超氧化物歧化酶的下调有助于心脏中的β-肾上腺素能受体介导的氧化胁迫

Downregulation of CuZn-superoxide dismutase contributes to β-adrenergic receptor-mediated oxidative stress in the heart

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