A new transmyocardial degradable stent combined with growth factor, heparin, and stem cells in acute myocardial infarction

Ying Wang12 Xiao-Cheng Liu12* Guang-Wei Zhang2 Jian Zhao12 Jie-Min Zhang2 Rong-Fang Shi3 Yun-Zhou Huang4 Chun-Hua Zhao5 Tian-Jun Liu6 Cun-Xian Song6 Feng Lü6 Qin Yang789 and Guo-Wei He789*

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A new transmyocardial degradable stent combined with growth factor, heparin, and stem cells in acute myocardial infarction

机译：新型心肌可降解支架结合生长因子，肝素和干细胞治疗急性心肌梗死

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Aims We developed a new method—transmyocardial drilling revascularization (TMDR) with absorbable stent incorporated with basic fibroblast growth factor (bFGF) and heparin. The present study tested the effect of this method with transplantation of bone marrow-derived stem cells (BMSCs) in acute myocardial infarction.

机译：目的我们开发了一种新方法-将可吸收支架与碱性成纤维细胞生长因子（bFGF）和肝素结合在一起，进行跨心肌钻探血运重建（TMDR）。本研究测试了这种方法与骨髓源性干细胞（BMSCs）在急性心肌梗死中的移植效果。

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《Cardiovascular Research》 |2009年第3期|p.461-469|共9页
作者
Ying Wang12 Xiao-Cheng Liu12* Guang-Wei Zhang2 Jian Zhao12 Jie-Min Zhang2 Rong-Fang Shi3 Yun-Zhou Huang4 Chun-Hua Zhao5 Tian-Jun Liu6 Cun-Xian Song6 Feng Lü6 Qin Yang789 and Guo-Wei He789*;
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作者单位

1Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China 2Department of Surgery, TEDA International Cardiovascular Hospital, No. 61, Third Avenue, TEDA, Tianjin 300457, China 3Department of Nuclear Medicine, TEDA International Cardiovascular Hospital, Tianjin, China 4Department of Ultrasound, TEDA International Cardiovascular Hospital, Tianjin, China 5Institute of Basic Medical Sciences, Center of Excellence in Tissue Engineering 6Institute of Biomedical Engineering, Peking Union Medical College, Beijing, China 7TEDA International Cardiovascular Hospital, Nankai University Medical College, Tianjin, China 8Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China 9Starr Academic Center, Providence Heart &

Vascular Institute, Oregon Health;

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1. A new transmyocardial degradable stent combined with growth factor, heparin, and stem cells in acute myocardial infarction [J] . WangY., LiuX.-C., ZhangG.-W., Cardiovascular Research . 2009,第3期

机译：新型心肌可降解支架结合生长因子，肝素和干细胞治疗急性心肌梗死
2. Mid-term effect of stem cells combined with transmyocardial degradable stent on swine model of acute myocardial infarction. [J] . Luan Y, Liu XC, Zhang GW, Coronary artery disease . 2010,第4期

机译：干细胞联合经心肌可降解支架对猪急性心肌梗死模型的中期效果。
3. Exosomes derived from miR‐146a‐modified adipose‐derived stem cells attenuate acute myocardial infarction?induced myocardial damage via downregulation of early growth response factor 1 Exosomes derived from miR‐146a‐modified adipose‐derived stem cells attenuate acute myocardial infarction?induced myocardial damage via downregulation of early growth response factor 1 [J] . Pan Junjie, Alimujiang Maimaitijiang, Chen Qiying, Journal of cellular biochemistry. . 2019,第3期

机译：衍生自MiR-146A改性的脂肪衍生的干细胞的外泌体衰减急性心肌梗死α诱导心肌损伤通过下调衍生自MiR-146A改性的脂肪衍生的干细胞的前期增长因子1 exosomes衰减急性心肌梗死？诱导心肌损伤通过早期生长响应因子1的下调
4. Extracellular matrix hydrogel as growth factor delivery system for prolonged release and enhanced effect of a novel engineered HGF mimic in a small animal model of myocardial infarction [C] . Sonya Sonnenberg, Aboli Rane, Vaibhav Bajaj, Society for Biomaterials annual meeting and exposition . 2013

机译：细胞外基质水凝胶作为生长因子递送系统，可在心肌梗塞的小动物模型中延长新型工程化HGF模拟物的释放并增强其作用
5. Evaluation of bone marrow derived stem cells in the treatment of acute myocardial infarction [D] . Davy, Philip M. C. 2011

机译：骨髓源性干细胞治疗急性心肌梗死的评估
6. Changes in circulating mesenchymal stem cells stem cell homing factor and vascular growth factors in patients with acute ST elevation myocardial infarction treated with primary percutaneous coronary intervention [O] . Y Wang, H E Johnsen, S Mortensen, 2006

机译：原发性经皮冠状动脉介入治疗急性ST段抬高型心肌梗死患者外周血间充质干细胞干细胞归巢因子和血管生长因子的变化
7. A new transmyocardial degradable stent combined with growth factor, heparin, and stem cells in acute myocardial infarction [O] . Y. Wang, X.-C. Liu, G.-W. Zhang, 2009

机译：一种新的透射性神经性可降解支架与生长因子，肝素和干细胞联合在急性心肌梗死中

A new transmyocardial degradable stent combined with growth factor, heparin, and stem cells in acute myocardial infarction

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