Effects of hypoxia-induced intrauterine growth restriction on cardiopulmonary structure and function during adulthood

摘要

Aims Intrauterine growth restriction (IUGR), a condition affecting 7–15% of all pregnancies, is associated with an increased mortality rate during adulthood. Several animal models have been developed to study the effects of IUGR during adulthood. However, the in vivo characteristics of these models are still unknown. The main aim of this work was to evaluate, in vivo, the effects of IUGR on cardiopulmonary structure and function during adulthood.