MTT assays cannot be utilized to study the effects of STI571/Gleevec on the viability of solid tumor cell lines

Jonathan T. Sims; Rina Plattner

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MTT assays cannot be utilized to study the effects of STI571/Gleevec on the viability of solid tumor cell lines

机译：MTT分析不能用于研究STI571 / Gleevec对实体瘤细胞系活力的影响

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Purpose This study will determine whether MTT assays accurately assess the effect of STI571 (Gleevec; Abl kinase inhibitor) on the viability of cancer cells containing highly active Abl kinases.

机译：目的这项研究将确定MTT分析是否能准确评估STI571（格列卫； Abl激酶抑制剂）对含有高活性Abl激酶的癌细胞生存能力的影响。

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《Cancer Chemotherapy and Pharmacology 》 |2009年第3期| p.629-633| 共5页
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Jonathan T. Sims; Rina Plattner;
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1. MTT assays cannot be utilized to study the effects of STI571/Gleevec on the viability of solid tumor cell lines. [J] . Sims JT, Plattner R Cancer chemotherapy and pharmacology. . 2009 ,第3期

机译：MTT分析不能用于研究STI571 / Gleevec对实体瘤细胞系生存力的影响。
2. A phase I dose-escalation study of imatinib mesylate (Gleevec/STI571) plus capecitabine (Xeloda) in advanced solid tumors. [J] . Dugan E, Truax R, Meadows KL, Anticancer Research: International Journal of Cancer Research and Treatment . 2010 ,第4期

机译：晚期实体瘤中甲磺酸伊马替尼（Gleevec / STI571）加卡培他滨（希罗达）的I期剂量递增研究。
3. Influence of serum and albumin on the in vitro anandamide cytotoxicity toward C6 glioma cells assessed by the MTT cell viability assay: Implications for the methodology of the MTT tests [J] . BilminK., KopczynskaB., GriebP. Folia neuropathologica . 2013 ,第1期

机译：MTT细胞生存力测定评估血清和白蛋白对C6胶质瘤细胞对体外anandamide细胞毒性的影响：MTT测试方法的含义
4. human Chorionic Gonadotropin and Deriveted-Angiotensin Peptides Effects on Cell Viability and on Apoptosis in Tumoral (MCF-7) and in Normal (MCF10A) Epithelial Breast Cells [C] . Alves Correa-Noronha S.A., Ribeiro de Noronha S.M., Shimuta S.I., International Congress on Cell Biology. . 2013

机译：人绒毛膜促性腺激素和衍生血管紧张素肽对细胞活力和肿瘤（MCF-7）和正常（MCF10A）上皮乳腺细胞的影响
5. Effects of Cloves and Ginseng Extracts on The Viability of Tumor Cell Lines [D] . Al Safar, Meshael F. 2016

机译：丁香和人参提取物对肿瘤细胞系活力的影响
6. MTT ASSAYS CANNOT BE UTILIZED TO STUDY THE EFFECTS OF STI571/GLEEVEC ON THE VIABILITY OF SOLID TUMOR CELL LINES [O] . Jonathan T. Sims, Rina Plattner -1

机译：MTT测定不能用于研究STI571 / GLEEVEC对实体肿瘤细胞系的活力的影响
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MTT assays cannot be utilized to study the effects of STI571/Gleevec on the viability of solid tumor cell lines

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