Plasma endothelin in patients with endotoxemia and dynamic comparison between vasoconstrictor and vasodilator in cirrhotic patients

摘要

Portal hypertension is a common clinical syndrome characterized by an abnormal increase in portal blood to the systemic circulation, bypassing the liver. Recent studies have reported that humoral substances play an important role in the pathogenesis of portal hypertension, either by increasing vascular resistance at both the intrahepatic and porto-collateral sites or affecting splanchnic vasodilation with a concomitant increase in parto-collateral blood flow~[1-6].