Methods for the diagnosis and Treatment of patients with critical illness, and the use of Endothelin and Endothelin agonists with vasoconstrictor activity in the preparation of drugs for the treatment of patients with critical illness

摘要

The ratio of the concentrations of immunoreactivity (proadm) / (proendotelina midregional pro end) in body Fluids of patients with critical illness are used for diagnosis, Monitoring and prognosis of the course, including the assessment of the risk of mortality, ENFE Rmedades severe life-threatening.In addition, Treatment of patients with critical illness with high levels of inmunorreactividades pro ADM but insufficient levels of pro - end with a drug that comprises by Endothelin vasoconstriction or their precursors and / or adrenomedullin Endothelin agonists or antagonists.