Study of apoptosis in human liver cancers

摘要

Conclusion: In vivo the apoptosis of carcinomas was lower; maybe the cells divided quickly and then the cancers occurred. In the cancer adjacent tissues, the apoptosis pricked up, and in vitro Solanum lyratun Thumb could induce the apoptosis of BEL-7404 cells. Aim: To investigate the action of apoptosis in occurrence of Liver cacinomas in vivo and the biological effect of Solanum Lyratum Thumb on BEL-7404 cell line linducing apoptosis in Vitro. Methods: The apoptosis in the liver caarcinoma was Detected with terminal deoxynucl neotidyl transferase Mediated dUTP nick end labelling(TUNEL); the cancer cells Cultured in DMED medium were treated with extract of Solanum lyratum Thumb and observed under microscope, And their DNA was assayed by gel electrophoresis.