Magnesium sulphate and pre-eclampsia

摘要

Magnesium sulphate has been used for treating" eclampsia in the United States for much of the 20th century. The international collaborative eclampsia trial confirmed that this anticonvulsant is indeed more effective, and safer, than alternative drugs. British obstetric practice has changed rapidly in response to these findings, and standard treatment of eclampsia in the United Kingdom now much more closely corresponds to that of the United States, although some controversies remain about optimal dosage.