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Effects of σ ligands on the nociceptin/orphanin FQ receptor co- expressed with the G-protein-activated K~+ channel in Xenopus oocytes

机译:σ配体对非洲爪蟾卵母细胞中与G蛋白激活的K〜+通道共表达的Nociceptin / Orphanin FQ受体的影响

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摘要

Taking advantage of the functionbal coupling or the nociceptin/orphanin FQ receptor with the G-protein- activated inwardly rectifying K~+(GIRK) channel, we investigated the effects of various σ ligands on the nociceptin/orphanin FQ receptor in Xenopus oocytes co-injected with the cloned nociceptin/orphanin FQ receptor and GIRK1 mRNAs.
机译:利用功能性偶联或伤害性感受器/孤儿蛋白FQ受体与G蛋白激活的内向整流K〜+(GIRK)通道,我们研究了各种σ配体对非洲爪蟾卵母细胞共伤害性感受器/孤儿素FQ受体的影响。注射克隆的痛觉敏/孤儿蛋白FQ受体和GIRK1 mRNA。

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