Faster growth and altered transcription induced transiently by 5-azacytidine in tobacco

摘要

Seedlings of Nicotiana tabaccum SR1 were treated with 5-azacytidine (5-azaC), a potent inhibitor of DNA methylation in vivo, resulting in retarded growth or death in some of the exposed plantlets. Following growth on drugless medium and later in soil under greenhouse conditions the treated plants developed faster and initiated flowering significantly earlier than the untreated controls. Among the F_1 progeny of the self-pollinated, treated plants a contin- uous transition was observed regarding flowering times: About 10/100 of the plants flowered as early as the F_0.