Usefulness of the simultaneous determination of serum levels of theophylline and its metabolites in patients medicated with theophylline preparation

摘要

Objective: Measurement of the serum level of theophylline is essential for its proper use; however, it is difficult to infer the metabolic ability of individual patients by only the serum theophylline level and to decide the appropriate medication. In this study, we simultaneously measured serum theophylline and metabolite levels in patients treated with theophylline, and investigated their usefulness.