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Characterisation of mega-voltage electron pencil beam dose distributions: viability of a measurement-based approach

机译:兆伏电子笔束剂量分布的表征:一种基于测量方法的可行性

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The concept of electron pencil-beam dose distributions is central to pencil-beam algorithms used in electron beam radiotherapy treatment planning. The Hogstrom algorithm, which is a common algorithm for electron treatment planning, models large electron field dose distributions by the superposition of a series of pencil beam dose distributions. This means that the accurate characterisation of an electron pencil beam is essential for the accuracy of the dose algorithm. The aim of this study was to evaluate a measurement based approach for obtaining electron pencil-beam dose distributions. The primary incentive for the study was the accurate calculation of dose distributions for narrow fields as traditional electron algorithms are generally inaccurate for such geometries. Kodak X-Omat radiographic film was used in a solid water phantom to measure the dose distribution of circular 12 MeV beams from a Varian 21EX linear accelerator. Measurements were made for beams of diameter, 1.5, 2, 4, 8, 16 and 32 mm. A blocked-field technique was used to subtract photon contamination in the beam. The "error function" derived from Fermi-Eyges Multiple Coulomb Scattering (MCS) theory for corresponding square fields was used to fit resulting dose distributions so that extrapolation down to a pencil beam distribution could be made. The Monte Carlo codes, BEAM and EGSnrc were used to simulate the experimental arrangement. The 8 mm beam dose distribution was also measured with TLD-100 microcubes. Agreement between film, TLD and Monte Carlo simulation results were found to be consistent with the spatial resolution used. The study has shown that it is possible to extrapolate narrow electron beam dose distributions down to a pencil beam dose distribution using the error function. However, due to experimental uncertainties and measurement difficulties, Monte Carlo is recommended as the method of choice for characterising electron pencil-beam dose distributions.
机译:电子笔束剂量分布的概念对于用于电子束放射治疗治疗计划的笔束算法至关重要。 Hogstrom算法是电子治疗计划的常用算法,它通过叠加一系列笔形电子束剂量分布来模拟大的电子场剂量分布。这意味着电子笔束的准确表征对于剂量算法的准确性至关重要。这项研究的目的是评估一种基于测量的方法来获得电子铅笔束的剂量分布。这项研究的主要动机是精确计算窄场的剂量分布,因为传统的电子算法通常对于这种几何形状是不准确的。将柯达X-Omat射线照相胶片用于固体水体模中,以测量来自Varian 21EX线性加速器的圆形12 MeV光束的剂量分布。对直径为1.5、2、4、8、16和32 mm的光束进行了测量。使用了阻塞场技术来减去光束中的光子污染。从费米·艾格斯多重库仑散射(MCS)理论得出的对应平方场的“误差函数”用于拟合最终的剂量分布,以便可以外推到笔形束分布。蒙特卡罗代码,BEAM和EGSnrc用于模拟实验安排。还使用TLD-100微立方体测量了8毫米光束的剂量分布。电影,TLD和蒙特卡洛模拟结果之间的一致性被发现与所使用的空间分辨率一致。研究表明,可以使用误差函数将狭窄的电子束剂量分布外推到笔形束剂量分布。但是,由于实验的不确定性和测量困难,建议使用Monte Carlo作为表征电子笔束剂量分布的选择方法。

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