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Ethnicity, housing and personal factors as determinants of VOC exposures

机译:种族,住房和个人因素是挥发性有机化合物暴露的决定因素

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Previous studies investigating effects of personal, demographic, housing and other factors on exposures to volatile organic compounds (VOC) have focused on mean or median exposures, and generally not the high exposures that are of great interest. This paper identifies determinants of personal VOC exposures on a quantile-specific basis using a nationally representative sample. The NHANES 1999-2000 VOC dataset was merged with personal, demographic, housing, smoking and occupation variables. Bivariate analyses tested for differences in geometric means and quantiles across levels of potential exposure determinants. Multivariate sample-weighted ordinary least-squares (OLS) and quantile regression (QR) models were then used to adjust for covariates. We identify a number of exposure determinants, most of which varied by exposure quantile. The most striking finding was the much higher exposures experienced by Hispanics and Blacks for aromatic VOCs (BTEX: benzene, toluene, ethylbenzene and xylenes), methyl tert-butyl ether (MTBE), and 1,4-dichlorobenzene (DCB). Exposure to gasoline, paints or glues, and having a machine-related occupation also were associated with extremely high BTEX and MTBE exposures. Additional determinants included the presence of attached garages and open windows, which affected exposures of BTEX (especially at lower quantiles) and MTBE (especially at higher quantiles). Smoking also increased BTEX exposures. DCB was associated with air freshener use, and PERC with dry-cleaned clothing. After adjusting for demographic, personal and housing factors, age and gender were not significant predictors of exposure. The use of QR in conjunction with OLS yields a more complete picture of exposure determinants, and identifies subpopulations and heterogeneous exposure groups in which some individuals experience very elevated exposures and which are not well represented by changes in the mean. The high exposures of Hispanics and Blacks are perplexing and disturbing, and they warrant further investigation.
机译:先前的调查研究个人,人口,住房和其他因素对挥发性有机化合物(VOC)暴露的影响的研究集中在平均暴露量或中位暴露量上,而通常不是人们非常感兴趣的高暴露量。本文使用具有国家代表性的样本,以分位数为基础确定个人VOC暴露的决定因素。 NHANES 1999-2000 VOC数据集已与个人,人口,住房,吸烟和职业变量合并。双变量分析测试了潜在暴露决定因素水平之间的几何平均值和分位数差异。然后使用多元样本加权普通最小二乘(OLS)和分位数回归(QR)模型来调整协变量。我们确定了许多暴露决定因素,其中大多数因暴露分位数而异。最引人注目的发现是西班牙裔和黑人对芳香族VOC(BTEX:苯,甲苯,乙苯和二甲苯),甲基叔丁基醚(MTBE)和1,4-二氯苯(DCB)的暴露量更高。暴露于汽油,油漆或胶水中以及与机器有关的职业也与极高的BTEX和MTBE暴露量相关。其他决定因素包括是否存在相连的车库和敞开的窗户,这会影响BTEX(尤其是较低分位数)和MTBE(尤其是较高分位数)的暴露。吸烟也增加了BTEX暴露。 DCB与空气清新剂的使用有关,而PERC与干洗衣服的使用有关。在调整了人口,个人和住房因素后,年龄和性别并不是暴露的重要预测指标。将QR与OLS结合使用可以更完整地了解暴露决定因素,并确定亚群和异类暴露组,其中某些个体的暴露水平非常高,而平均值变化并不能很好地代表这些人群。西班牙裔美国人和黑人的高暴露令人困惑和不安,需要进一步调查。

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