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Air-guided photonic-crystal-fiber pulse-compression delivery of multimegawatt femtosecond laser output for nonlinear-optical imaging and neurosurgery

机译:兆瓦飞秒激光输出的空气引导光子晶体光纤脉冲压缩输出,用于非线性光学成像和神经外科手术

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摘要

Large-core hollow photonic-crystal fibers (PCFs) are shown to enable a fiber-format air-guided delivery of ultrashort infrared laser pulses for neurosurgery and nonlinear-optical imaging. With an appropriate dispersion precompensation, an anomalously dispersive 15-μm-core hollow PCF compresses 510-fs, 1070-nm light pulses to a pulse width of about 110 fs, providing a peak power in excess of 5 MW. The compressed PCF output is employed to induce a local photodisruption of corpus callosum tissues in mouse brain and is used to generate the third harmonic in brain tissues, which is captured by the PCF and delivered to a detector through the PCF cladding.
机译:大芯空心光子晶体光纤(PCF)可以实现超短红外激光脉冲的纤维格式空气引导递送,用于神经外科手术和非线性光学成像。通过适当的色散预补偿,异常分散的15μm芯空心PCF将510fs,1070nm的光脉冲压缩到大约110fs的脉冲宽度,从而提供超过5 MW的峰值功率。压缩的PCF输出用于在小鼠大脑中诱导induce体组织的局部光破坏,并用于在脑组织中生成三次谐波,该三次谐波被PCF捕获并通过PCF包层传递到检测器。

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  • 来源
    《Applied Physics Letters》 |2012年第10期|p.101104.1-101104.4|共4页
  • 作者单位

    Physics Department, International Laser Center, M.V. Lomonosov Moscow State University, Moscow 119992,Russia;

    Physics Department, International Laser Center, M.V. Lomonosov Moscow State University, Moscow 119992,Russia,Department of Neuroscience, Kurchatov National Research Center, Moscow, Russia;

    Physics Department, International Laser Center, M.V. Lomonosov Moscow State University, Moscow 119992,Russia;

    Physics Department, International Laser Center, M.V. Lomonosov Moscow State University, Moscow 119992,Russia,Department of Neuroscience, Kurchatov National Research Center, Moscow, Russia;

    Department of Neuroscience, Kurchatov National Research Center, Moscow, Russia,P.K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia;

    Department of Neuroscience, Kurchatov National Research Center, Moscow, Russia,P.K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia;

    Graduate Institute of Photonics and Optoelectronics and Department of Electrical Engineering,National Taiwan University, Taipei 10617, Taiwan;

    Department of Physics, Bilkent University, Cankaya, Ankara 06800, Turkey;

    Physics Department, International Laser Center, M.V. Lomonosov Moscow State University, Moscow 119992,Russia,Department of Neuroscience, Kurchatov National Research Center, Moscow, Russia;

    Department of Neuroscience, Kurchatov National Research Center, Moscow, Russia,P.K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia;

    Physics Department, International Laser Center, M.V. Lomonosov Moscow State University, Moscow 119992,Russia,Department of Neuroscience, Kurchatov National Research Center, Moscow, Russia,Department of Physics and Astronomy, Texas A&M University, College Station, Texas 77843, USA;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
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  • 正文语种 eng
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  • 入库时间 2022-08-18 03:17:07

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