Peyer's Patch Dendritic Cells Capturing Oral Antigen Interact with Antigen-Specific T Cells and Induce Gut-Homing CD4~+CD25~+ Regulatory T Cells in Peyer's Patches

摘要

Antigen-specific naive T cells accumulated in Peyer's patches only after the feeding of antigen. DCs that captured oral antigen interacted with these T cells in the IFR of PP. Some of these T cells acquired a similar pheno-type to CD4~+ CD25~+ regulatory T cells and CCR9~+ gut-homing T cells.