Preoperative Chemoradiotherapy (Modified Eilber Protocol) Provides Maximum Local Control and Minimal Morbidity in Patients With Soft Tissue Sarcoma

Lloyd A. Mack MD; Phil J. Crowe MD; Jia Lin Yang MEd; PhD; Norman S. Schachar MD; Don G. Morris MD; PhD; Elizabeth C. Kurien MD; Claire L. F. Temple MD; Robert L. Lindsay MD; Enzio Magi MD; William G. DeHaas MD; Walley J. Temple MD; FRCSC; FACS

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Preoperative Chemoradiotherapy (Modified Eilber Protocol) Provides Maximum Local Control and Minimal Morbidity in Patients With Soft Tissue Sarcoma

机译：术前放化疗（改良的Eilber方案）可为软组织肉瘤患者提供最大的局部控制和最低的发病率

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Local recurrence rates of 15% to 30% after treatment of soft tissue sarcoma (STS) are still common but unacceptable. Our hypothesis was that a refined neoadjuvant chemotherapy and radiation protocol (modified Eilber protocol) improves local control rates while minimizing major morbidity.

机译：治疗软组织肉瘤（STS）后局部复发率为15％至30％仍然很普遍，但不可接受。我们的假设是，完善的新辅助化疗和放疗方案（改良的Eilber方案）可提高局部控制率，同时最大程度地降低主要发病率。

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来源
《Annals of Surgical Oncology》 |2005年第8期|646-653|共8页
作者
Lloyd A. Mack MD; Phil J. Crowe MD; Jia Lin Yang MEd; PhD; Norman S. Schachar MD; Don G. Morris MD; PhD; Elizabeth C. Kurien MD; Claire L. F. Temple MD; Robert L. Lindsay MD; Enzio Magi MD; William G. DeHaas MD; Walley J. Temple MD; FRCSC; FACS;
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作者单位

Division of Surgical Oncology University of Calgary Tom Baker Cancer Centre 1331 29th Street N.W. Calgary Alberta Canada T2N 4N2;

Department of Surgery University of New South Wales Prince of Wales Hospital High Street Randwick New South Wales 2031 Australia;

Department of Surgery University of New South Wales Prince of Wales Hospital High Street Randwick New South Wales 2031 Australia;

Department of Surgery University of CalgaryFoothills Medical Centre 1403 29th Street N. W. Calgary Alberta T2N 2T9 Canada;

Division of Surgical Oncology University of Calgary Tom Baker Cancer Centre 1331 29th Street N.W. Calgary Alberta Canada T2N 4N2;

Division of Surgical Oncology University of Calgary Tom Baker Cancer Centre 1331 29th Street N.W. Calgary Alberta Canada T2N 4N2;

Department of Surgery University of CalgaryFoothills Medical Centre 1403 29th Street N. W. Calgary Alberta T2N 2T9 Canada;

Department of Surgery University of CalgaryFoothills Medical Centre 1403 29th Street N. W. Calgary Alberta T2N 2T9 Canada;

Department of Surgery University of CalgaryFoothills Medical Centre 1403 29th Street N. W. Calgary Alberta T2N 2T9 Canada;

Department of Surgery University of CalgaryFoothills Medical Centre 1403 29th Street N. W. Calgary Alberta T2N 2T9 Canada;

Division of Surgical Oncology University of Calgary Tom Baker Cancer Centre 1331 29th Street N.W. Calgary Alberta Canada T2N 4N2;

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正文语种 eng
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关键词
Soft tissue sarcoma; Limb-sparing surgery; Combined-modality therapy; Local control.;

机译：软组织肉瘤;保肢手术;联合疗法;局部控制;

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专利

1. Preoperative chemoradiotherapy (modified Eilber protocol) provides maximum local control and minimal morbidity in patients with soft tissue sarcoma. [J] . Mack LA, Crowe PJ, Yang JL, Annals of surgical oncology . 2005,第8期

机译：术前放化疗（改良的Eilber方案）可为软组织肉瘤患者提供最大的局部控制和最低的发病率。
2. Primary tumor necrosis predicts distant control in locally advanced soft-tissue sarcomas after preoperative concurrent chemoradiotherapy. [J] . MacDermed DM, Miller LL, Peabody TD, International Journal of Radiation Oncology, Biology, Physics . 2010,第4期

机译：术前同时放化疗后，原发性肿瘤坏死预示着局部晚期软组织肉瘤的远程控制。
3. CORR Insights((R)): Does an Algorithmic Approach to Using Brachytherapy and External Beam Radiation Result in Good Function, Local Control Rates, and Low Morbidity in Patients With Extremity Soft Tissue Sarcoma? [J] . Healey John H. Clinical Orthopaedics and Related Research . 2018,第3期

机译：Corr Insights（（r））：使用近距离放射治疗和外光辐射的算法方法是否导致患者患者的良好功能，局部控制率和患者的低发病率？
4. Computer-enhanced preoperative planning of soft tissue sarcoma surgery [C] . Raposio, E., Norat, . 2002

机译：软组织肉瘤手术的计算机增强术前计划
5. Near-Infrared Spectroscopy to Assess Exercise-Induced Changes in Skeletal Muscle Oxygenation in Patients with Soft Tissue Sarcoma: A Preliminary Investigation [D] . Hoselton, Andrew Lewis. 2021

机译：近红外光谱，评估软组织肉瘤患者骨骼肌氧合的运动诱导的变化：初步调查
6. Primary Tumor Necrosis Predicts Distant Control in Locally Advanced Soft Tissue Sarcomas Following Preoperative Concurrent Chemoradiotherapy [O] . Dhara M. MacDermed, Luke L. Miller, Terrance D. Peabody, -1

机译：在术前同时化学疗法之后原发性肿瘤坏死预测局部先进的软组织肉瘤中的远处控制
7. Primary Tumor Necrosis Predicts Distant Control in Locally Advanced Soft-Tissue Sarcomas After Preoperative Concurrent Chemoradiotherapy [O] . Dhara M. MacDermed, Luke L. Miller, Terrance D. Peabody, 2010

机译：原发性肿瘤坏死预测术前同时化疗后局部先进的软组织肉瘤中的远处控制

Preoperative Chemoradiotherapy (Modified Eilber Protocol) Provides Maximum Local Control and Minimal Morbidity in Patients With Soft Tissue Sarcoma

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