Impact of p53 expression and microsatellite instability on stage III colon cancer disease-free survival in patients treatedn         by 5-fluorouracil and leucovorin with or without oxaliplatin

F. Praz

首页> 外文期刊>Annals of Oncology >Impact of p53 expression and microsatellite instability on stage III colon cancer disease-free survival in patients treatedn by 5-fluorouracil and leucovorin with or without oxaliplatin

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Impact of p53 expression and microsatellite instability on stage III colon cancer disease-free survival in patients treatedn by 5-fluorouracil and leucovorin with or without oxaliplatin

机译：5-氟尿嘧啶和亚叶酸钙联合或不联合奥沙利铂治疗的患者中p53表达和微卫星不稳定性对III期结肠癌无病生存的影响

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Background: The aim was to determine the values of p53 tumour expression and microsatellite instability (MSI) phenotype to predict benefit from adjuvant chemotherapy of colon cancer by 5-fluorouracil and leucovorin (FL) alone or with oxaliplatin (FOLFOX).

机译：背景：目的是确定p53肿瘤表达和微卫星不稳定性（MSI）表型的值，以预测单独使用5-氟尿嘧啶和亚叶酸（FL）或与奥沙利铂（FOLFOX）联合使用结肠癌的辅助化疗获益。

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《Annals of Oncology》 |2010年第4期|p.772-780|共9页
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1. Impact of p53 expression and microsatellite instability on stage III colon cancer disease-free survival in patients treated by 5-fluorouracil and leucovorin with or without oxaliplatin. [J] . Zaanan A, Cuilliere Dartigues P, Guilloux A, Annals of oncology: official journal of the European Society for Medical Oncology . 2010,第4期

机译：p53表达和微卫星不稳定性对5-氟尿嘧啶和亚叶酸钙联合或不联合奥沙利铂治疗的III期结肠癌无病生存的影响。
2. Microsatellite Instability was not Associated with Survival in Stage III Colon Cancer Treated with Adjuvant Chemotherapy of Oxaliplatin and Infusional 5-Fluorouracil and Leucovorin (FOLFOX) [J] . Kim Jeong Eun, Hong Yong Sang, Kim Hwa Jung, Annals of surgical oncology . 2017,第5期

机译：微卫星不稳定性与氧化剂化疗治疗的III阶段结肠癌的存活率无关，奥沙利铂和流入5-氟尿嘧啶（Folfox）治疗
3. Determination of TP53 Mutation Is More Relevant Than Microsatellite Instability Status for the Prediction of Disease-Free Survival in Adjuvant-Treated Stage III Colon Cancer Patients. [J] . Westra JL, Schaapveld M, Hollema H, Journal of Clinical Oncology . 2005,第24期

机译：TP53突变的测定与微卫星不稳定性状态的相关性更高，可用于预测辅助治疗的III期结肠癌患者的无病生存期。
4. Adjuvant Chemotherapy Should Not Routinely Be Recommended to Patients with Stage II Colon Cancers that Manifest Microsatellite Instability [C] . Sigurdis Haraldsdottir, Richard M. Goldberg Gastrointestinal Cancers Symposium . 2014

机译：不应常规向患有阶段结肠癌的患者常规的辅助化学疗法，表明微卫星不稳定性
5. Early stage breast cancer and comorbidities: Their impact on breast cancer disease-free survival differences by ethnicity. [D] . Guerra, Sandra Lee. 2010

机译：早期乳腺癌和合并症：种族对乳腺癌无病生存率差异的影响。
6. Effect of Oxaliplatin Fluorouracil and Leucovorin With or Without Cetuximab on Survival Among Patients With Resected Stage III Colon Cancer [O] . Steven R. Alberts, Daniel J. Sargent, Suresh Nair, -1

机译：影响奥沙利铂氟尿嘧啶亚叶酸钙和带或不带西妥昔单抗对生存的患者中切除的III期结肠癌
7. Two or three year disease-free survival (DFS) as a primary end-point in stage III adjuvant colon cancer trials with fluoropyrimidines with or without oxaliplatin or irinotecan: Data from 129676 patients from MOSAIC, X-ACT, PETACC-3, C-06, C-07 and C89803 [O] . Sargent, D, Shi, Q, Yothers, G, 2011

机译：含或不含奥沙利铂或伊立替康的氟嘧啶类药物在二期或三年无病生存期（DFS）作为III期辅助结肠癌试验的主要终点：来自MOSAIC，X-ACT，PETACC-3，C- 06，C-07和C89803

Impact of p53 expression and microsatellite instability on stage III colon cancer disease-free survival in patients treatedn by 5-fluorouracil and leucovorin with or without oxaliplatin

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