Thyroptropin and thyroid antibodies as predictors of hypothyroidism: a 13-year, longitudinal study of a community-based cohort using immunoassay techniques

摘要

The upper limit of the thyroid-stimulating hormone (TSH)nreference range is controversial. Historically, values havenbeen based on 95% confidence intervals of log-transformednconcentrations obtained from healthy individuals. Anpaucity of longitudinal studies examining the associationnbetween baseline TSH and development of hypothyroidismnexists.