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A Finite Volume Method for Modeling Discontinuous Electrical Activation in Cardiac Tissue

机译:心脏组织中不连续电激活建模的有限体积方法

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摘要

This paper describes a finite volume method for modeling electrical activation in a sample of cardiac tissue using the bidomain equations. Microstructural features to the level of cleavage planes between sheets of myocardial fibers in the tissue are explicitly represented. The key features of this implementation compared to previous modeling are that it represents physical discontinuities without the implicit removal of intracellular volume and it generates linear systems of equations that are computationally efficient to construct and solve. Results obtained using this method highlight how the understanding of discontinuous activation in cardiac tissue can form a basis for better understanding defibrillation processes and experimental recordings.
机译:本文介绍了一种有限体积方法,用于使用双畴方程对心脏组织样本中的电激活进行建模。组织中心肌纤维片之间的分裂平面水平的微结构特征被明确表示。与以前的建模相比,此实现的关键特征是它表示物理间断而没有隐式去除细胞内体积,并且生成了方程组的线性系统,这些方程组在计算和构造上都非常有效。使用这种方法获得的结果强调了对心脏组织中不连续激活的理解如何可以为更好地理解除颤过程和实验记录奠定基础。

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